| ncRNA name | ZNF503-AS1 |
| ncRNA Category | lncRNA |
| ID | 253264 |
| Ensembl | ENSG00000226051 |
| Synonyms | NA |
| Disease name | age-related macular degeneration (AMD) |
| Species | Homo sapiens |
| Tissues/Cell_line | human induced pluripotent stem cells (hiPSCs), hiPSC-derived RPE cells (hiPSC-RPE) |
| Methods | microarray, RT-PCR, qPCR, Fluorescent in situ hybridization, transfection, immunoblot, immunofluorescent staining |
| Expression pattern | up-regulated |
| Functional description | ZNF503-AS1 potentially promotes RPE differentiation through downregulation of ZNF503 expression. In addition, nuclear factor-κB was recognized as a potential upstream transcript factor for ZNF503-AS1, which might participate in promoting RPE differentiation by regulating the expression of ZNF503-AS1. |
| PubMed ID | 28880276 |
| Year | 2017 |
| Title | LncRNA ZNF503-AS1 promotes RPE differentiation by downregulating ZNF503 expression. |
| Drug-related ncRNA | NO |
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